Fine Lines & Wrinkles

Smooth, firm skin — powered by prescription retinoids

Fine lines and wrinkles develop as collagen production slows and sun damage accumulates. Prescription tretinoin is the only topical ingredient proven to rebuild collagen and reverse visible aging. Combined with Obagi's skin-brightening system, the result is smoother, firmer, more youthful skin.

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Recommended Treatments

Prescription products selected for fine lines & wrinkles concerns.

Obagi Tretinoin Cream

The gold standard for wrinkle reduction

$65/monthView details

Obagi Nu-Derm Blender Rx

Evens tone for a more youthful complexion

$95/monthView details

Concerns We Treat

Crow's feet

Fine lines around the eyes caused by repeated expressions and UV exposure.

Forehead lines

Horizontal creases across the forehead that deepen with age.

Nasolabial folds

Lines running from the nose to the corners of the mouth — also called smile lines.

Neck lines

Horizontal creases and crepey texture on the neck that reveal aging.

How It Works

Complete a skin health questionnaire with close-up photos

A licensed provider evaluates your wrinkle concerns and prescribes treatment

Your Obagi regimen is shipped directly to your door

Apply nightly and see smoother skin in 4–8 weeks

Frequently Asked Questions

Can tretinoin really reduce wrinkles?

Yes — tretinoin is the only topical with decades of clinical evidence showing it rebuilds collagen, thickens the skin, and smooths fine lines. It's the dermatologist's #1 recommendation.

What's the difference between tretinoin and retinol?

Tretinoin is prescription-strength and works directly on skin cells. Retinol is weaker and must be converted to retinoic acid in the skin first, making it far less effective for wrinkle reduction.

How long before wrinkles improve?

Fine lines often soften in 4–6 weeks. Deeper wrinkles require 3–6+ months of consistent use. Collagen rebuilding is a gradual process.

Can I use Botox and tretinoin together?

Yes — many dermatologists recommend using both. Botox addresses dynamic wrinkles (from movement), while tretinoin improves skin texture, tone, and static lines.

Start reducing wrinkles with prescription tretinoin

Complete a free consultation and get your Obagi prescription shipped in days.

Get Started

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Smooth, firm skin — powered by prescription retinoids

Free Shipping Ships in 3–5 days HIPAA Compliant

Frequently Asked Questions

Can tretinoin really reduce wrinkles?

Yes — tretinoin is the only topical with decades of clinical evidence showing it rebuilds collagen, thickens the skin, and smooths fine lines. It's the dermatologist's #1 recommendation.

What's the difference between tretinoin and retinol?

Tretinoin is prescription-strength and works directly on skin cells. Retinol is weaker and must be converted to retinoic acid in the skin first, making it far less effective for wrinkle reduction.

How long before wrinkles improve?

Fine lines often soften in 4–6 weeks. Deeper wrinkles require 3–6+ months of consistent use. Collagen rebuilding is a gradual process.

Can I use Botox and tretinoin together?

Yes — many dermatologists recommend using both. Botox addresses dynamic wrinkles (from movement), while tretinoin improves skin texture, tone, and static lines.

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Smooth, firm skin — powered by prescription retinoids

Recommended Treatments

Obagi Tretinoin Cream

Obagi Nu-Derm Blender Rx

Concerns We Treat

Crow's feet

Forehead lines

Nasolabial folds

Neck lines

How It Works

Frequently Asked Questions

Start reducing wrinkles with prescription tretinoin

Smooth, firm skin — powered by prescription retinoids

Recommended Treatments

Obagi Tretinoin Cream

Obagi Nu-Derm Blender Rx

Concerns We Treat

Crow's feet

Forehead lines

Nasolabial folds

Neck lines

How It Works

Frequently Asked Questions

Start reducing wrinkles with prescription tretinoin